mRNA-based vaccines and therapeutics offer a promising approach to addressing unmet needs in disease prevention and treatment. Explore a simple, robust workflow for IVT, the gold standard method for large-scale production of mRNA drug substances.
Discover how IVT streamlines plasmid purification, RNA production, and quality control of the purified nucleic acids.
Download the application note for data-rich information about:
- An automated workflow for IVT of mRNA
- Automated plasmid purification and quality control
- Plasmid-directed IVT of RNA on magnetic beads (solid-phase IVT)
- Quality control of purified RNA by direct sequencing and quantification by PCR
- Precise measurement of residual template DNA in purified RNA samples by dPCR