The Limits of Traditional Neurodegenerative Trial Design

Dear Kenneth,

Neurodegenerative disease trials present persistent challenges—from long study durations and progressive disability to high participant burden and limited sensitivity of site-based assessments.

As digital health technologies mature, they are enabling new ways to observe disease progression through continuous, real-world data capture. At the same time, evolving regulatory frameworks are creating clearer pathways for integrating these tools into trial design.

This white paper explores:

  • Why conventional trial models struggle to capture nuanced neurological change
  • How digital health technologies support more continuous, patient-centric data collection
  • Where decentralized and hybrid approaches can improve accessibility without compromising rigor

Download the report to explore how digital health is reshaping neurodegenerative clinical trials.

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